Research Specialist - Sharma Lab
Job Description
Posting Number
PG194214SPInternal Recruitment
NoWorking Title
Research Specialist - Sharma LabAnticipated Hiring Range
$45,454-$48,000Work Schedule
Monday-Friday, 8:00am - 5:00pm. This position may require weekend, night, and holiday hours.Job Location
Raleigh, NCDepartment
Department of Population Health and PathobiologyAbout the Department
The mission of the Department of Population Health and Pathobiology is to recruit, train, inspire, and graduate Doctors of Veterinary Medicine of exemplary knowledge, skill, and character. In order to maintain the intellectual and professional climate necessary to accomplish this mission, the department’s faculty will advance veterinary medical science through innovative basic and applied research, inspired mentoring of students (undergraduate, professional, residents, and graduate), excellence in clinical and diagnostic services, and innovative extension and engagement activities.
North Carolina State University’s College of Veterinary Medicine (CVM) is a dynamic community whose members are dedicated to preparing veterinarians and veterinarian scientists while advancing animal and human health from the cellular level through entire ecosystems. The College has gained international recognition on the strength of its teaching, research, engagement, and patient care efforts and is ranked 3rd among the nation’s 28 colleges of veterinary medicine in the current U.S. News & World Report survey.
Located on 180 acres near downtown Raleigh, the College encompasses 20 buildings on the main Centennial Biomedical Campus. Instruction is in three departments—Clinical Sciences, Molecular Biomedical Sciences, and Population Health Pathobiology. In addition to the four-year Doctor of Veterinary Medicine degree, there are programs leading to master and doctoral degrees in several areas with numerous opportunities for specialization.
North Carolina State University’s College of Veterinary Medicine (CVM) is a dynamic community whose members are dedicated to preparing veterinarians and veterinarian scientists while advancing animal and human health from the cellular level through entire ecosystems. The College has gained international recognition on the strength of its teaching, research, engagement, and patient care efforts and is ranked 3rd among the nation’s 28 colleges of veterinary medicine in the current U.S. News & World Report survey.
Located on 180 acres near downtown Raleigh, the College encompasses 20 buildings on the main Centennial Biomedical Campus. Instruction is in three departments—Clinical Sciences, Molecular Biomedical Sciences, and Population Health Pathobiology. In addition to the four-year Doctor of Veterinary Medicine degree, there are programs leading to master and doctoral degrees in several areas with numerous opportunities for specialization.
This unit’s goal is promote enhanced multidisciplinary digestive disease research.
Essential Job Duties
Research Focus: Infectious Diseases
The Research Specialist will join Dr. Amit Sharma’s lab, which focuses on:
- Investigating the host innate immune response as a barrier to cross-species retrovirus transmission in non-human primates.
- Studying neutralization and inhibitors of SARS-CoV-2 entry.
Role Overview
Under the mentorship of the Principal Investigator (PI), the Research Specialist will:
Under the mentorship of the Principal Investigator (PI), the Research Specialist will:
- Characterize viral and host factors that influence the selection, adaptation, and pathogenicity of SHIVs in macaque cells ex vivo.
- Explore the molecular and mechanistic basis of SHIV adaptation to the macaque immune response.
- Conduct virus neutralization assays and develop engineered peptides and peptidomimetic-based compounds targeting SARS-CoV-2, including rationally designed ACE2 inhibitors.
Responsibilities
- 80% Research:
- Participate in experimental research on innate immune responses as barriers to retrovirus transmission in non-human primates.
- Characterize viral and host factors influencing SHIV adaptation in macaque cells.
- Perform virus neutralization assays and evaluate peptide-based compounds for SARS-CoV-2.
- Generate experimental data for publications, ongoing/future grant proposals, and pursue independent funding opportunities.
- 15% Writing:
- Assist in preparing research reports, manuscripts, presentations, and seminars to communicate research progress.
- 5% Lab Management:
- Perform organizational and lab duties as needed.
Minimum Experience/Education
Bachelor’s degree in a discipline related to the area of assignment; or an equivalent combination of training and experience.
All degrees must be received from appropriately accredited institutions.
Other Required Qualifications
- Hands on experience with tissue culture of cell lines.
- Routine maintenance of cell lines.
- Emphasis on molecular biology techniques including PCR, RT-qPCR, RNA extraction,
- Protein purification, Primer designing, and DNA sequence analysis.
- Skilled in immunological techniques like Plate Reader-based Enzyme linked
- immunosorbent assay, Western blot, and Flow cytometry.
- Training in BSL2 safety.
- Training in GraphPad Prism and data analyses.
Preferred Qualifications
N/A
Required License or Certification
N/A
Valid NC Driver's License required
NoCommercial Driver's License Required?
NoJob Open Date
09/05/2024Earliest Close Date---- (Positions will be posted until 5:00 PM ET on this date. Positions remaining posted after this date are still accepting applications but may close at any time.)
09/11/2024Special Instructions
Please include a cover letter, resume/CV, and contact information for professional references.
Position Number
00111033Position Type
SHRAPosition Classification Band Title
Research SpecialistPosition Classification Band Level
ContributingPosition Classification Salary Range
$ 45,454 - $ 109,409Salary Grade Equivalency
GN08Alternate Option
If no applicants apply who meet the required competency level and training & experience requirements, then management may consider other applicants. Salary would be determined based on competencies, equity, budget, and market considerations.
Full Time Equivalent (FTE) (1.0 = 40 hours/week)
1.0Appointment
12 Month RecurringMandatory Designation - Adverse Weather
Non Mandatory - Adverse WeatherMandatory Designation - Emergency Events
Non Mandatory - Emergency EventTime Limited Position
NoDepartment Id
196001 - Dept-Population,Health,PathobiAA/EEO
NC State University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, gender identity, age, sexual orientation, genetic information, status as an individual with a disability, or status as a protected veteran. Individuals with disabilities requiring disability-related accommodations in the application and interview process are welcome to contact 919-515-3148 to speak with a representative at the Office of Institutional Equity and Diversity.
If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or workatncstate@ncsu.edu.
Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.
NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.
If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or workatncstate@ncsu.edu.
Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.
NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.
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